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69 Injection site pain occurred most commonly early in treatment, associated with the AL NCD and/or the first AL injection

10.1037/a0029057 331 KlusekJ.MartinG

doi:10.1016/j.cca.2010.05.026

[29, 30, 31] They can be delivered alone or in combination with immunomodulatory agents

Another research found the mitochondrial DNA (mtDNA) mutation G3842A injures mitochondrial complex I, influences oxygen consumption and ATP production and elevates ROS levels, thus activating ERK1/2 signaling and facilitating carcinogenesis [234]