why do glp 1 cause diarrhea Exploring the Side Effects of GLP-1 Receptor Agonist: To Ensure Its Optimal Positioning can a glp 1 cause
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No significant difference in semaglutide plasma concentration across the four groups was observed and adverse events were similar across groups
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A study in 1,500 Danish subjects suggested that the GLP-1 response to oral glucose is reduced in patients with prediabetes or type-2 diabetes [262]

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For the newer-generation therapies there was increased risk of nausea compared with placebo: semaglutide relative risk (RR) 2.95 (95% CI 2.613.32), tirzepatide RR 2.90 (95% CI 24.19), and orforglipron RR 4.77 (95% CI 2.0211.31)

Primary Handling Editor: Christoph Schmitt, in collaboration with the Nature Metabolism editorial team
