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Second, cell-type and stone-subtype heterogeneity is largely ignored: current studies have focused solely on HK-2 cells, while the role of ferroptosis in other renal resident cells (e.g., renal interstitial cells and collecting duct cells) or infiltrating immune cells during stone formation is unknown

Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy

And the point Im bringing is that the vote itself isnt really the whole story

The Scientific World Journal 2012, 2012:792756