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After the muscle biopsy the following baseline assessments were performed: upper and lower (stronger non-biopsied leg) extremity strength testing by dynamometry and the 6-min walk test, RAND SF-36 questionnaire, and Stanford exercise behavior scale

In an attempt to increase the NADH/NAD+ ratio and rescue cell viability, the MAS was inhibited by treatment with aminooxyacetic acid (AOA) that broadly inhibits transaminases including the aspartate aminotransferase of the MAS ( Fig

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Marrocco V, et al

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In the current study, PTZ was found to decrease NE, DA, and 5-HT levels in both the hippocampus and hypothalamus regions