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The reason: since the fragment contains only the C-terminal part, it lacks the binding domains for GHR (most of the affinity of hGH for GHR lies in the central part of the molecule)

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Its well-documented profile provides a reliable foundation for generating reproducible data

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Therefore, we hypothesize that perhaps the reason for unresponsive surgeries could be due to the stimulation site rather than the efficacy of DBS itself [62]