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In conclusion, treatment with once-weekly subcutaneous semaglutide in conjunction with behavioral intervention in adults with overweight (with at least one weight-related comorbidity) or obesity (without diabetes) was associated with clinically impactful and sustained weight loss of 15.2% at week 104, along with improvements in weight-related cardiometabolic risk factors

After synthesizing the specific biomarkers, a solid-phase extraction protocol and a UHPLC-MS/MS method with isotopic dilution were optimized

Petersburg Institute of Bioregulation and Gerontology, primarily under the direction of Vladimir Khavinson

Sisk LM, Gee DG

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2.5.1.3 Intact hCG analysis Samples purported to contain hCG were subjected to direct LC-QTOF-MS/MS analysis without prior pretreatment