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Description
Power NE
Regulatory and Ethical Challenges Despite positive regulatory movements, inconsistencies across regions, particularly in Asia Pacific and Europe, create approval delays and complicate global commercialization strategies
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Parkinsongenic agents 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) (known to destroy the dopamine nigrostriatal system by formation of free radicals) (30.0 mg/kg b.w., i.p
This determination was based on chronic toxicity studies, genotoxicity studies, and human clinical trial safety data
2019;122:e10207
