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In the adult clinical trial, the median levels of serum vitamin E, ALA, linoleic acid, EPA, DHA, and arachidonic acid (AA) decreased from baseline to Week 26 but remained above the lower limit of the reference range

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The finding that neutralization of reactive lipid carbonyls with 2-AMPs effectively reduces atherosclerosis and improves HDL function in atherosclerotic mouse models offers promise of beneficial treatment of CAD in humans