l'carnitine amino acid Carnitine L-Carnitine Amino Acid | Natural

KD and KB are capable to increase mitochondrial respiration via an increase in ATP production and improve the efficiency of the mitochondrial respiratory chain complex with increased mitochondrial biogenesis (69)

Jan-Feb 1988;105(1-2):45-9

Exp Gerontol (2020) 132:110841

Paulis et al., 2017)

Ophthalmology 114, 23662367

In addition, the ERGO-induced microglial M2 polarization may further suppress TDP43 aggregation since microglial activation is related to the aggregation, and M2 microglia especially are more efficient phagocytes for brain wastes than M1 microglia [35, 72, 73] TDP43 activates microglia through NF-B and NLRP3 inflammasome [70], and the impaired microglial phagocytosis of dying neurons may contribute to the formation of pathological TDP43 [74]