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The tyloxapol model reproduces a pathophysiological state characterised by impaired lipid clearance due to LPL inhibition and consequent hepatic lipid overproduction (lipogenesis), a combination that underlies dyslipidaemia and non-alcoholic fatty liver disease (Reference Packard, Boren and Taskinen4Reference Tocto-Chaquila, Tarrillo-Peralta and Vega-Huamn7)

In those cases, surgical or combined approaches offer better improvement

Luganini, A., Boschi, D., Lolli, M

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H., Norwitz, E