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The cofactors like selenium, zinc, copper of many enzymes may be replaced by lead, and thereby, resulting in enzyme inactivation

Yang J, Yan Y, Liu H, Wang J, Hu J

OH can react/bind with purine and pyrimidine bases of nucleic acids and chromatin proteins, resulting in genomic instability and chromosome modifications that alter the expressions of different genes

E.HenriquesM

Protein expression profiling shows high glycolysis and oxidative metabolism along with the pentose phosphate pathway rendering certain growth advantages in breast cancer brain metastasis

"Subacute Combined Degeneration of the Spinal Cord"
