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MR-PRESSO detected outliers in the overall associations with CAD in FinnGen (shown in Additional file 1: Table S5), where we used corrected estimates from MR-PRESSO

The twist is that a subset of gut bacteria can chew on L-carnitine and related nutrients and make a small volatile compound called trimethylamine or TMA

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As expected, the contents of pAMPK and pACC in the l-carnitine group were significantly increased compared with those in the LPS group, and l-carnitine increased the level of ATP

Schandene, L

This process also highlights why deficiencies in L-Carnitine can have significant effects, particularly in conditions like PCOS