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doi: 10.1016/j.atherosclerosis.2011.10.027

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In a single photon emission tomography (SPECT) study, RLS severity was found to be increased when there was decreased availability of serotonin transporters in the pons and medulla

Taddei, A., Maison, C., Roche, D

T.WoolrichM.MatthewsP

The tumor-derived cytokines such as vascular endothelial growth factor (VEGF), endothelin-1 (ET1), EGF-like domain-containing protein 7 (EGFL7), and fibroblast growth factor 2 (FGF2) downregulate gene expression and protein expression of adhesion molecules and chemoattractants (e.g., CCL2, CXCL10, and CXCL7) resulting into inhibition of the immune cell infiltration (69)
