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Platonov, I

"Some people are deficient and feel a lot better when given a shot, but just to pep you up, there's no study that says it's helpful." B12 is created by bacteria, including those living in the digestive tract
[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Zhang J, Zhao L, Hu C, Wang T, Lu J, Wu C, Chen L, Jin M, Hu H, Ji G, Cao Q, Jiang Y.Fisetin prevents acetaminophen-induced liver injury by promoting autophagy

LPC activates peroxisome proliferator-activated receptor gamma (PPAR), a transcription factor required for M2 polarization, which in turn increases Major Histocompatibility Complex, Class I-Related (MR1), chitinase 3-like 3 (Ym1), IL-10 and TGF, but not Nitric Oxide Synthase 2 (NOS2), gene expression, which is characteristic for M2 macrophages (50)

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In addition, LA not only reduced the cellular iron overload by upregulating the expressions of Ferritin and ferroportin (FPN), but also mitigated reactive oxygen species (ROS) accumulation and lipid peroxidation by increasing the levels of antioxidant glutathione (GSH) and glutathione peroxidase-4 (GPX4)
