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After entering the cochlea, cisplatin is taken up into cells by diffusive and passive transport, copper transporter protein 1 (Ctr1) and organic cation transporter protein 2 (OCT2), endocytosis, and toxicity through DNA adduct formation, oxidative stress, mitochondrial dysfunction, inflammatory response, and ferroptosis (Elmorsy et al., 2024)

M.LaterraJ.JosephA.JinL.FuchsA.WayD.et al (1996)

J Clin Invest (2011) 121:401529

Difference Between Glutathione Shots Administration and Other Cosmetic Procedures Glutathione shots are different from other skin therapies as they have an active agent that is a strong and potent antioxidant

And my response was pretty simple: Holy cow

Most newly synthesized membrane-bound and secreted proteins are co-translationally translocated into the ER lumen, where they undergo critical post-translational modifications and proper folding to ensure correct trafficking and functionality