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Journal of Analytical Toxicology, 25(4):245249, Malayala SV et al (2022): Xylazine-Induced Skin Ulcers in a Person Who Injects Drugs in Philadelphia, Pennsylvania, USA
It interacts with DNA to form adductssuch as DNADNA and DNAproteins crosslinkswhich activate several signal transduction pathways that trigger cell death 74,76
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Tumor necrosis factor (TNF) induces NFB and AP-1 nuclear-binding activities and both are required for normal expression of both GCL subunits and GS in rat
