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S., Abdelaziz, M
Targeting multiple stages of the viral life cycle (such as entry, replication, and assembly) through multitarget drug design can help mitigate the risk of resistance
This form is responsible for maintaining the glutathione redox cycle in the cytoplasm, where numerous metabolic processes generate reactive oxygen species during normal cellular respiration and enzymatic reactions
A mammalian variant of GST, GSTP, plays a major role in cancer- development and potential drug/chemotherapeutic resistance in a majority of tumor cell lines: The inhibition of the pro-apoptotic pathway (JNK pathway) and the overexpression of GSTP in tumor cells lead to escape of apoptosis of the tumor cells mediated by non GSTP- substance-drugs Hayes et al.,1995 Josephy,2010 Hayes et al.,2000 Fraser et al.,2003
Expression patterns of the creatine metabolism-related molecules AGAT, GAMT and CT1 in adult zebrafish Danio rerio
J.ChlipalaG.MohneyR
