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Dysregulation will persist to enhance autoreactive T cell activation and lead to disease progression and exacerbation ( Changes in the gut microbiota can significantly impact the production of short-chain fatty acids (SCFAs) and other metabolites which in turn modulate systemic inflammation and immunity

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doi: 10.1523/JNEUROSCI.20-15-j0006.2000 85

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However, current TCM research in PCOS primarily focuses on the general modulation of the gut microbiota, with limited attention given to ferroptosis-specific mechanisms