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& Pugin, A
In alcohol-exposed rats, no change in agonist-induced GTPS binding was observed (Kufahl et al., 2011), whereas the ability of the same mGlu 2/3 agonist to reduce extracellular glutamate levels in vivo was reduced (Meinhardt et al., 2013)
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Notably, no tolerance development was observed during the treatment periods, and no rebound insomnia occurred after discontinuation
Always consult a licensed healthcare provider before beginning any peptide protocol
doi: 10.1016/s0006-8993(02)03290-0
