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Unfortunately, many of these anticonvulsants have no known or limited beneficial effects on pain management in clinical trials (Rao et al., 2007, 2008

One other mechanism involved is via its effect on aquaporin-1 water channels, present in the apical and basolateral membrane of cholangiocytes [9]

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More interestingly, such PI-tolerance of B-ALL cells can be transmitted to sensitive cells by releasing exosomes (Ge et al., 2020)

Supporting liver detoxification: The liver relies on glutathione to process and eliminate toxins, making it essential for healthy detox pathways