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Hepatic metabolism research has examined Retatrutides influence on liver fat markers in pre-clinical models of non-alcoholic fatty liver disease, with studies exploring how combined GLP-1, GIP, and glucagon receptor activation affects hepatic lipid handling compared to dual-receptor compounds

[6] [13] Proton pump inhibitors (PPIs) and H2-receptor antagonists , used for acid reflux, reduce stomach acid production and may affect B12 release from food proteins

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