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These include: Metformin (used for diabetes or PCOS) Proton Pump Inhibitors (used for acid reflux or GERD) H2 Blockers Birth control pills Certain antibiotics If youre taking these medications long-term, particularly in combination, regular B12 injections might be beneficial

doi: 10.1021/acs.jmedchem.9b01255

112 pmol/L ( n = 119), P 0.30 for tests of interaction)

Early human trials showed a promising signal that a larger pivotal trial did not replicate, and the compound today sits in an unusual regulatory position: GRAS-designated as a food ingredient, but not an approved drug

As wellness experts, we recognize the importance of addressing neurological symptoms associated with vitamin B12 deficiency, including numbness and tingling sensations in the hands and feet

Intravenous B12 therapy is used in certain cases