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Ran-GTP closes the importin solenoid We elucidated the cryo-EM structure of the importin :Ran-GTP complex at a resolution of 3.34 (Supplementary Fig

Ascorbic acid inhibits senescence in mesenchymal stem cells through ROS and AKT/mTOR signaling

including adult patients with either T1D or T2D treating with mecasermin rinfabate (12 mg/kg/day for 14 days) showed lowered exogenous insulin requirements while improving glycaemic control

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Lysosomal acid lipase hydrolyzes retinyl ester and affects retinoid turnover

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