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A., Thakkar A
A2AR adenosine signaling suppresses natural killer cell maturation in the tumor MicroenvironmentAdenosine impairs proliferation of terminal NK cells
This was further supported by gene set analysis which indicated IR most potently regulated of metabolic pathways (glucose, pyruvate and cholesterol metabolism), as well as genes in the hypoxia inducible factor and protein turnover pathways, and genes implicated in diabetes (Supplementary Table 2)
Zang QS, Sadek H, Maass DL, Martinez B, Ma L, Kilgore JA, et al
Finally, presumably receptor-mediated inhibition of D2 activity by T3 has been demonstrated in pituitary tumor cells (83), and D2 mRNA levels in brain, pituitary and BAT are up-regulated in hypothyroid rats and down-regulated in hyperthyroid animals (84, 85)
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