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For larger tumors involving these structures controversy exists on whether the benefits of a complete resection, namely a reduction in the risk of recurrence/progression, are outweighed by the surgical morbidity particularly hypothalamic obesity, visual impairment, and adipsic diabetes insipidus (190,191)

A 2.5 mg dose of tirzepatide and a 0.25 mg dose of semaglutide are both "starting doses" that serve the same purpose, tolerance building, but the actual pharmacology behind each number is unique

How sublingual tirzepatide fits into the broader GLP-1 landscape Sublingual tirzepatide does not exist in isolation

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doi: 10.3389/fendo.2013.00158 Received 12 August 2013 Accepted 09 October 2013 Published 25 October 2013 Volume 4 - 2013 Edited by Walmor De Mello, University of Puerto Rico, USA Reviewed by Maria Christina W