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165 CCR2 which is the only receptor for (MCP-1/CCL2 recruits inflammatory cells to lungs in COPD, and increases synthesis of MUC5AC and MUC5B

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The doses chosen were because higher doses of cagrilintide may be associated with gastrointestinal adverse effects, in particular nausea and vomiting, and require dose escalation to be attained

In instances where Nrf2 is inhibited, heightened FOCAD expression suppresses colony formation, migration, and invasive capacity of cancer cells (Brockschmidt et al., 2012

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