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The first is that glucose-induced desensitization is due to the glucose insensibility of the -cell
Methylglyoxal-induced functionality loss of mural cells Mural cells of the brain microvasculature refer to the pericytes and VSMCs, which surround the BMECs [10]

Other actions have also been described, such as restoring the response of immune cells, modulating the inflammatory response, counteracting the thrombotic state, and exerting an antiviral effect [4]

In recent investigations, LNPs have demonstrated a huge potential in delivering CRISPR/Cas9 components to target cells
Polyethyleneimine-based nanocarriers for gene delivery
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