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After a single therapeutic dose of acetaminophen, APAP glucuronidation was significantly influenced by the UGT2B15*2 polymorphism and very modestly by the UGT1A6*2 genotype

The oxidation steps, utilizing glucose-6-phosphate (G6P) as the substrate, occur at the beginning of the pathway and are the reactions that generate NADPH

M., Komaroff, A

J Hum Clin Gen

AIC and BIC model selection criteria were deployed to suggest which model is mechanistically important, guided by the OCR data
