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Description
O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy
Indian J Cancer 29(1):27-30, 1992
Cranial magnetic resonance imaging showed a wide range of long T1 and T2 signals in the bilateral frontotemporal parietal lobes and short T1 signals in the bilateral pallidum (81)
10.1002/jnr.23307 123
While the mechanism is well-characterized and the animal results are impressive, human dosing protocols are based on extrapolation rather than controlled clinical evidence
The future of clinical research in neuroscience, therefore, lies in collecting real-world data and using them as catalysts for clinical trial design and in further development of individually-tailored treatment procedures
