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Repici M, Giorgini F
The dense extracellular matrix (ECM) excessively secreted by PSC creates a physical hurdle that contributes to increased interstitial fluid pressure 10 , impaired hemoperfusion 11 , cellular hypoxia 12 , and blockage of nutrient and drug delivery 13
10.1007/s00726-010-0777-y 81 NehligA.Wittendorp-RechenmannE.LamC
Nitric oxide dilates blood vessels, enabling greater blood flow and oxygen uptake into working muscles, supporting exercise performance
S.PedrosaM.DiamondR.et al (1998)
Fox summarizes key takeaways
