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This is because hypokalemia and thrombocytosis could occur due to the increase in erythrocyte metabolism following vitamin B12 therapy

At this juncture, Phase II conjugation reactions, and in particular glutathione-dependent pathways are crucial, as they enable detoxification and promote the subsequent excretion of these reactive species

27 Moreover, in many diseases, GSH plasma and whole blood levels are not correlated

Pregnancy & breastfeeding: Insufficient safety data exists

Furthermore, elevated levels of ROS have been associated with a decrease in meiotic completion 34, 35 and age-associated phenotypes including altered spindle microtubules, chromosome misalignment 36,37,38 , aneuploidy 15, 39 and diminishing embryo developmental potential 32, 40,41,42,43,44

The expression level of the ARID1A protein may vary depending on the cell context