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Higher rates of toxicity were reported in patients receiving ramucirumab treatment ( Tyrosine Kinase Inhibitors Tyrosine kinase inhibitors (TKIs) are small molecules that inhibit the kinase domain of RTKs thus inhibiting receptor activation and downstream signaling ( Sorafenib Sorafenib (Nexavar ) is an oral multikinase inhibitor of VEGFR, PDGF receptor (PDGFR), and Raf (Pitoia and Jerkovich, 2016)

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Gestational choline can impact the methylation of promoter DNA to regulate the expression of key epigenetic enzymes in brain cells [42,43]

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To evaluate whether 0.8 mM GDC-treated monolayers were biocompatible with digested food, IMF was subjected to in vitro infant gastrointestinal digestion