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It is notable that previous studies have suggested that the chrM:302 site serves as a rheostat for mtDNA replication versus transcription, which are functionally linked in mitochondria 3,45
This regulatory pattern is similar to what has been observed with xCT, as previous studies have reported that xCT expression can be induced by inflammatory stimuli, including substances like LPS and TNF
[DOI] [PMC free article] [PubMed] [Google Scholar] Shi J., Huang M.W., Lu Z.D., Du X.J., Shen S., Xu C.F., Wang J
[PMID: 10940574]
Post final wash, the supernatant was removed and 25 l of 4x SDS loading buffer was added to the beads and heated for 5 mins at 95 C
doi: 10.1007/s10555-020-09896-5 135 SokolovaONaumannM
