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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Keller J, Ringseis R, Eder K

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Cocea A-C, Stoica CI (2024) Interactions and trends of interleukins, PAI-1, CRP, and TNF- in inflammatory responses during the perioperative period of joint arthroplasty: implications for pain managementa narrative review

it hydrolyzes NAD + to deacetylate target proteins while concurrently moving the lysine-bound acetyl group from acetylated proteins to both 2-O-acetyl-ADP-ribose and nicotinamide, which are produced by the 2-OH position of ADA-ribose (Figure 1B