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In December 2024, the FDA's Pharmacy Compounding Advisory Committee declined to include it on the 503A bulk drug substances list, meaning compounding pharmacies in the United States cannot legally produce it for individual prescriptions

After 2 weeks I stretched with arms back and felt shoulder pop back into place

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Due to endorsements from celebrities and influencers, its become a popular supplement in more recent years

The mechanism is scientifically sound and consistently supported by animal data, but human efficacy and safety have not been established through clinical trials