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IFNs bind to cell surface receptors that are associated with janus kinases (JAK), which then phosphorylate intracellular receptor chains, generating docking sites for the signal transducer and activator of transcription (STAT

[DOI] [PMC free article] [PubMed] [Google Scholar] [100].Bartolini D, Stabile AM, Bastianelli S, Giustarini D, Pierucci S, Busti C, et al

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Structures of lazaroids are shown in Figure 8

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It is also a common reason for drugs to be withdrawn from the market