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B12 deficiency can be found in dogs and cats with IBD and B12 supplements are given to help

Restores dendritic spines In a mouse hippocampal neuron model of Alzheimer's amyloid toxicity, EDR (200 ng/mL) increased mushroom dendritic spines by 71%, returning the parameter close to normal (Kraskovskaya et al., 2017)

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Hydroxy works but I have to cycle on and off and can tip the scales quit easily