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Following the use of SAM in methyl transfer reactions, the resultant S-adenosylhomocysteine (SAH or AdoHcy) is hydrolyzed by adenosylhomocyteinase (also called S-adenosylhomocysteine hydrolase) to yield homocysteine and adenosine

doi: 10.1110/ps.0243403

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Additionally, the long-term effects of these compounds are not yet fully understood, so caution should be exercised with their use

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