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Pins and needles The sensation of pins and needles, also known as paresthesia, in some limbs of the body could also be due to the deficiency of vitamin b12

Environmental agents including air pollutants and airway infection are the major trigger of exacerbations

doi: 10.1182/blood.2019000944 77 MaS.WangD.XieD

Nigrosome 1 has been found to be the first and most severe site of dopaminergic neuron loss in PD, which is found in the caudal mid-lateral part of the midbrain SNpc

Montine KS, Quinn JF, Zhang J, Fessel JP, Roberts LJ 2nd, Morrow JD, Montine TJ (2004) Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases