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Results COX-2 deteriorated hepatocyte morphology under both TAA and erastin treatments Under intraperitoneal TAA challenge, the liver structure of COX-2 +/+ mice, as revealed by HE staining, underwent significant changes, characterized by inflammatory cell infiltration and fibrotic septa formation in the liver tissue

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Therefore, targeting planktonic bacteria is critical for early containment of biofilm formation

doi:10.1016/j.bbamcr.2015.01.021