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Acknowledgements This study was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan, Japan Heart Foundation Grant for Research on Hypertension and Metabolism, and a Grant for Research Foundation for Community Medicine

Skin lightening is a term used to describe reducing hyperpigmentation, dark spots, melasma, age spots, or birthmarks so that the skin tone is even in color

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The results showed a significant 40% increase in skin elasticity compared to placebo, accompanied by improved skin texture confirmed by histological analysis, which revealed reduced solar elastosis and a reorganization of collagen fibers