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It also can reduce the levels of glutathione, which could affect the guts antioxidant capacity and thus increase the risk of the development of diseases, such as inflammatory bowel disease

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Other research has indicated that copper deficiency inhibits the expression of adhesion molecules, while activating endothelial cells through inducing leukocyte adhesion (105)

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Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle