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Description
Utilising the PICO (population, intervention, control, and outcome) framework, the target population for this review was patients with acute and stable PD, the main interventions looked at were any non-surgical treatments, these were compared to control groups who had not received the relevant non-surgical treatment option and outcomes looked at included improvement in penile curvature, plaque size, pain, sexual function, and penile length

J Physiol 596(19):4753-65 2018 PMC6166047 Rhea EM, Nirkhe S, Nguyen S, Pemberton S, Bammler TK, Beyer R, Niehoff ML, Morley JE, Farr SA, Banks WA

Additionally, a water molecule interacts with R471 and Q207 (TM4), connecting the carboxylate to the N-terminal bundle

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Recent Findings Conservative therapy with intralesional collagenase clostridium histolyticum (CCH) is safe and efficacious in either the acute or chronic phases of PD

Guideri, F., Acampa, M., Hayek, Y
