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Firstly, long-chain fatty acids are converted to long-chain acyl-CoA catalyzed by acyl-CoA synthetases in the endoplasmic reticulum and outer mitochondrial membrane

All five components of the C1 complex showed strongly enhanced binding to both MSU crystals and PC-agarose in the presence of CRP

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Hancock, D.L

doi:10.1043/2011-0051-RAIR.1 (PubMed PMID: 21732771)