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[13] For the liver side specifically, researchers use hepatocyte lipid-loading models (exposing primary human hepatocytes or HepG2 cells to fatty acids such as oleate and palmitate to induce steatosis in a dish), hepatic stellate-cell lines (for example LX-2) to study fibrogenic activation, and increasingly three-dimensional systems liver organoids, spheroids, and liver-on-a-chip devices that better reproduce cellcell interactions

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Abstract This case report documents a self-directed recovery from a complex, chronic multisystem condition consistent with Gu syndrome, involving Candida overgrowth, dysbiotic flora consistent with small intestinal bacterial overgrowth (SIBO), mold toxicity, intestinal hyperpermeability (leaky gut), and significant microbiome disruption

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