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Molecular Bases of the CFTR Defect CFTR is a unique member of the ATP-binding cassette (ABC) transporters family that acts as an ATP-gated low conductance chloride-selective channel

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Sheared genomic DNA was purified with 0.8 Superior AMPure XP Alternative (12601ES08, Yeasen) and end repair, dA-tail, adaptor ligation, AMPure XP bead purification, PCR enrichment, and PCR product purification were performed using the DNA Library Prep Kit (Novogene) with minor modifications to the manufacturers protocol

Peptides are short chains of amino acids, the building blocks of proteins, that play vital roles in various physiological processes in the body