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Acknowledgements The current research was funded by the European Union Seventh Framework Programme HeCaToS (FP7/2007-2013) under the Grant Agreement No

Generally, for maintaining GSH homeostasis in brain, there are at least two possible mechanisms: (i) glutathione constituents (cysteine moieties) may be recovered and recycled during the turnover of GSH in the brain, and (ii) precursors for brain glutathione synthesis (cysteine, cysteine-containing molecules) might be transported across the blood-brain barrier [13]

NK cells originate from hematopoietic stem cells in the bone marrow and are among the core cells of the innate immune system, accounting for approximately 5%15% of all immune cells in the blood

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