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Common side effects Here are some common side effects near the injection site that are mild and usually go away within 1 to 2 weeks: Rare side effects Here are some more rare but serious side effects: Potential medical emergency Seek emergency medical attention if you experience any of the following conditions or their related symptoms: infection filler leaking out of the injection site growths or nodules that appear near the injection site inflammatory growths called granulomas filler moving out of the injection area to other nearby areas of the face blood vessel injury losing vision from filler being injected into arteries that supply blood to your eyes death of facial tissue from blood flow blockage While the Food and Drug Administration (FDA) has approved several dermal fillers, they havent approved any of them specifically for use in the temples

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However, this skin disorder is common in people with diabetes who inject insulin subcutaneously every day

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It is studied in experimental models for effects on body composition, lipolysis, and IGF-1 modulation without significant cortisol or prolactin elevation.