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This review focuses on the evaluation of patients with elevated CK without significant muscle-related symptoms and proposes an algorithm for this purpose ( Figure 1 )

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Bibcode:1990BBRC..168.1118C

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In preclinical research models, MT-2 has been characterized for its agonism at MC1R (the receptor governing melanocyte eumelanin synthesis) and at MC4R (a central receptor studied in energy-homeostasis and melanocortin-signaling research)