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Moreover, results from animal studies have consistently demonstrated the detrimental effects of oxidative stress on central nervous system 15,16

Recommended Dosage Modifications for Adverse Reactions: Myelosuppressive toxicity: ANC less than 500 cells/mm3 AND platelets at least 50,000 cells/mm3 OR platelet count less than 50,000 cells/mm3 without bleeding: Dose for next cycle should be 75% of previous dose

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administered by a healthcare professional. Purpose of the Injection Administration Code This code compensates the provider for preparation, patient education, administration, observation, and documentation of the injection

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